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Showing posts with label POVERTY & LEARNING. Show all posts
Showing posts with label POVERTY & LEARNING. Show all posts

How an innovative grants program (and Belgian beer mixers) at Johns Hopkins fuels discoveries about the human brain

Written By Unknown on Monday, February 2, 2015 | 2:06 AM



A neuroscientist, an electrical engineer, a surgeon, and an education researcher walk up to a bar.

This could be the start of a joke, or it could be a scene from a recent Science of Learning Institute event at Johns Hopkins University. At the institute's four-times-yearly Belgian Beer Events, scientists from far-flung fields—and often from far-flung parts of the university itself—present their research to each other in short, digestible chunks. Their creativity and conviviality stimulated by a cup of ale or lager, the researchers strike up conversations and form connections that range widely across disciplinary boundaries, from classroom learning to machine learning, from recovery from stroke to memory formation in the brain.

Such conversations can be all too rare at a university where faculty are spread not just across a campus but throughout a large city and beyond. The result, for an inherently interdisciplinary subject like the science of learning, is that projects that could address fundamental and important questions can be hard to conceive and get off the ground. And too often, promising basic research doesn't get translated into the settings where it could help real-world learners.

The Belgian Beer Events, conceived shortly after the institute launched in 2013, are helping change that. They provide an informal space where basic researchers can meet translators, where machine-learning experts can meet early-childhood educators, where cognitive scientists can meet smartphone app developers. The events rotate between locations: October's was at the School of Education, and December's was hosted by the Department of Biomedical Engineering; previous ones were held at the School of Medicine and in Homewood's Levering Hall. Computer scientist Greg Hager likens the events to "an intellectual mixing bowl."

Beyond generating lively conversation, the gatherings are sparking collaborations between researchers who otherwise might never have met. At an event in 2013, neurologist Bonnie Nozari presented her work on speech and language processing disorders. Computer scientist Raman Arora then spoke about his work on machine learning and speech recognition. Recognizing a mutual interest in speech, the two chatted. The next day, they began planning a joint project to see if computers can predict how humans will pronounce words, and then provide feedback to people seeking to learn a new language, or to relearn how to speak after a stroke.

It sounds like a lucky encounter, but in fact electrical engineer Sanjeev Khudanpur, a member of the institute's steering committee, was at work behind the scenes. He conceived the Belgian Beer Events, and he made sure that Arora, his colleague in the Whiting School of Engineering, would be speaking on the same day as Nozari, of the School of Medicine. Later, when the two were ready to apply for funding, Khudanpur encouraged their ultimately successful proposal for one of the institute's research grants. "I see myself as a matchmaker," he says.

"It's that kind of really innovative, different seeding of projects that I think we've done really well," says Barbara Landau, the institute's director and the Dick and Lydia Todd Professor of Cognitive Science in the Krieger School of Arts and Sciences. The institute funded eight projects in 2013 and eight more in 2014, with projects receiving an average of $140,000 spread over two years. Funding goes to hiring graduate students and postdoctoral researchers, developing software, purchasing equipment, and supplying other research needs. The grants are competitive; the review committee has received around 30 proposals a year. The funded projects address a broad range of learning settings, from the classroom to the operating room to distance learning that can take place anywhere. The learners are not limited to humans, either; many of the projects include a strong component of "machine learning"—harnessing computers to recognize patterns in data and use them to develop new human learning applications. Other projects focus on developing animal models that can be used to study human learning.

The grant program allows researchers to get support for projects that might not be quite ready for a proposal to a traditional funding agency like the National Science Foundation or the National Institutes of Health, says Landau. Almost without exception, an NSF or NIH review panel will want to see at least preliminary data demonstrating that an idea is viable. With Science of Learning Institute funding, scientists can do exploratory research that will provide the data needed to support a larger proposal to a more traditional funding agency. "It allows people to do things that they wouldn't necessarily be able to accomplish by a standard grant," says Landau. "The granting agencies tend to be somewhat conservative, and we're looking for innovation."

Like Arora and Nozari's collaboration, many of the funded projects harness existing technological applications to improve learning, often in novel ways. For example, Khudanpur and Hager are working with Gyusung Lee, an instructor of surgery in the School of Medicine, to develop computer software that can help teach surgeons how to use the da Vinci robotic surgical platform. The project grew out of an existing effort called the Language of Surgery, developed by researchers in the Whiting School of Engineering's Laboratory for Computational Sensing and Robotics.

Through this effort, which began in 2006, Hager, Khudanpur, and colleagues program computers to record and analyze the different kinds of movements that surgeons make while performing certain tasks with surgical robots. The researchers' goal was to find movements that could consistently be classified as either expertlike or novicelike. Novice surgeons are more likely to break a suture, for example, or to push or pull on tissue while using the robot to manipulate a surgical needle. The researchers were able to train computer software to recognize such expert and novice movements much as a surgical trainer would.

The next step is to have the assessment tool provide real-time feedback to surgical trainees. With the kind of application the researchers are envisioning, trainees could, in theory, receive an unlimited amount of individualized feedback on what skills they have mastered and where more work is needed. "We're putting the computer in the human learning loop," Khudanpur says. "The computer has certain abilities that are complementary to humans. [For example,] the computer doesn't get tired. The computer usually doesn't charge by the hour."

A few years ago, when the researchers applied for an NIH grant to develop such a learning application, the proposal was rejected because they had no data showing the idea had promise. Thanks to their Science of Learning Institute research award, the scientists are starting to collect that data. Backed by some preliminary results, they recently put in a new NIH proposal and are waiting to hear back.

Meanwhile, thanks to a talk Hager gave last fall, his team's research may soon spawn another effort, which would take Language of Surgery technology out of the operating room and into the classroom. Hager's presentation inspired Landau and Amy Shelton, a professor in the School of Education, who is also on the institute's steering committee, to wonder whether motion-tracking software could recognize the movements that young children make when learning to build toy towers out of blocks. Spatial skills like tower building, in addition to being important in their own right, are of interest to researchers because they often predict children's future abilities in math and other areas. Hager, Landau, and Shelton are now discussing a potential project to put motion sensors on blocks and use computers to track how children acquire manipulation skills, a tactic similar to the one Hager's team uses to assess the skills of aspiring surgeons.

Institute-funded collaborations between computer scientists and education researchers are also reaching far beyond traditional education settings like medical training. In a project funded in 2014, computer scientists Philipp Koehn and Jason Eisner are teaming with Chadia Abras in the School of Education's Center for Technology Education to develop a radically new way to learn a foreign language. The idea is based on macaronic language—a kind of text that mixes two languages into a Spanglish-like hybrid. While such mixing has traditionally been employed by novice speakers or for satirical purposes, Eisner realized that coupled with recent advances in machine translation, it could also help introduce learners to foreign vocabulary and syntax in a gentle and piecemeal way rather than all at once, as in a typical foreign text read laboriously with the aid of a dictionary.

To implement the idea, the researchers are developing software that translates a text progressively, with more and more of the text appearing in the foreign language as the reader's comprehension improves. For an English-to-German learner, for instance, the English phrase "a loaf of bread" could start to appear as "ein Loaf of Bread." When the reader is comfortable with reading the German word "ein" instead of the English "a," the program could progress to "ein Breadloaf," resembling German in syntax but retaining English words. The text would then become "ein Brot loaf," and finally the fully German "ein Brotlaib*." The program will intermittently assess the student's reading comprehension and ability, and tune the amount of foreign language presented to the reader's progress; readers also can direct the program to make the translation easier or harder.

Since the concept still needs to be proved, it makes an ideal Science of Learning Institute project, says Koehn. Eisner adds, "It's a bet that this will work out and will not, for example, confuse people or give them bad habits." The researchers plan to develop an English-to-German application and test it on the Web and in Johns Hopkins classes in combination with more traditional classroom and textbook instruction. If successful, the software could also be made available on the Internet for independent learners.

The project exemplifies how interdisciplinary teams can merge cutting-edge research in machine and human learning, says Kelly Fisher, the institute's assistant director and an assistant professor in the School of Education. "It's a software program that is learning itself, learning about the learner."

Institute-funded research also targets learners far beyond those who are acquiring skills for the first time. Learning is critical for the millions of people who lose skills when they suffer strokes and other neurological conditions and then need to regain them, often through lengthy and complex rehabilitation processes. Research on how to more efficiently relearn lost skills could make a huge difference in how quickly such people can return to work and fully participate in society again.

Cognitive scientist Michael McCloskey recently discovered a new, debilitating, and apparently very rare reading deficit known as alphanumeric visual awareness deficit, or AVAD. McCloskey, a professor in Cognitive Science, identified the condition based on two cases that came to him in one year. One of them, a 61-year-old Baltimore geologist with a neurological disease, could see fine in general, but when looking at letters or numbers, he saw only blurs. McCloskey and his colleagues found, however, that by teaching the patient new characters to use in place of the digits, they could restore his recognition abilities. The researchers developed a smartphone calculator app and modified the geologist's laptop to allow him to do math with the new symbols.

Seeking to build on this work, McCloskey assembled a team of neurologists and cognitive scientists to look for more people with AVAD in order to study the condition using brain imaging and other techniques, and to develop apps and other technology that would help affected people make sense of letters and numbers again. But the researchers have run into a roadblock: They haven't found a single other case of AVAD beyond the original two. A woman in North Carolina who seemed to have the deficit turned out to have a somewhat different condition. "On the one hand, it's interesting that [AVAD is] so rare; on the other hand, it's not what we were hoping for," McCloskey says.

So he and his team have reoriented their project, broadening the scope to include more-common character recognition disorders. For example, some people cannot recognize a number or letter when it is presented to them whole but can recognize a character if they watch it being drawn. Perhaps, says McCloskey, a smartphone app could be developed to read signs and other important text, and draw each character in sequence for people with this deficit. His team is also starting to collaborate with a software developer, MicroBLINK, to make an app that would identify characters and then read the text aloud.

In addition to potentially helping people regain lost abilities, many institute-funded projects such as McCloskey's are aimed at teasing apart the different brain regions and processes responsible for seemingly coherent learned skills like reading. Along these lines but focusing on an entirely different brain function, psychologist Marina Bedny, of the Krieger School's Department of Psychological and Brain Sciences, is heading a team that received an institute grant to study how the brain can retool its hardware when the original purpose of one of its regions is no longer needed. In sighted people, around a quarter of the brain is devoted to visual processing; in blind people, these brain regions get repurposed. How does this work? Bedny wondered.

To investigate this question, she and colleagues in the Krieger School's Department of Cognitive Science and in the Department of Physical Medicine and Rehabilitation at the School of Medicine are combining language comprehension assessments with a technique called transcranial magnetic stimulation, or TMS. They hope to learn whether brain regions normally devoted to sight are needed for language processing in blind people. The researchers recently collected data at a National Federation of the Blind convention and are in the process of testing a control group of sighted people. This effort would have been impossible without a source of support for interdisciplinary projects, Bedny says. "You just can't do this kind of research without an interdisciplinary team because you need so many different kinds of expertise," from linguistics to neuroimaging to TMS. "We really needed the whole team to make it happen."

In another example of institute-funded brain research, neuroscientist David Foster, of the School of Medicine, is taking on perhaps the most basic of all aspects of learning: memory formation. Specifically, Foster is interested in how certain kinds of memories are formed in a brain region called the hippocampus. He has studied this process in detail in rat brains, using dozens of implanted electrodes to precisely record electrical signals as the rats' neurons fire in sequences that represent stored memories. Foster would like to carry out similar studies in humans, but he cannot just go sticking electrodes deep into people's brains. So he first needs to develop less-invasive procedures.

Foster and William Anderson, an associate professor of neurosurgery in the School of Medicine, are now developing such techniques, piggybacking on research that Anderson's group does on epilepsy patients wherein they collect and analyze electrical data gathered from the surface of the brain. By piloting their study on a small sample of patients, the researchers hope to strengthen their position for applying for a larger grant, possibly from the NIH.

Bedny and Foster, both assistant professors, say that institute funding has allowed them to take on projects that might have otherwise been too risky and uncertain for an untenured faculty member. "I probably would not do too much looking outside of my own area to collaborate if I wasn't pushed and incentivized to do so by this kind of mechanism," Foster says. "This allows me, and pays me, to invest in thinking outside of my own small area."

The research grant program is the Science of Learning Institute's first major initiative, and many of the projects from the initial funding round are close to reporting results. The institute plans to continue awarding grants for at least three more years, and possibly more, depending on funding. To assess the program's success, Landau and Fisher are tracking metrics such as publications that awardees produce and external awards that leverage institute-funded work.

The institute also just launched its second big initiative: the Distinguished Science of Learning Fellowship Program. This program will award around five postdoctoral and predoctoral fellowships annually to students wanting to pursue interdisciplinary research in learning. Each fellow will have two advisers from different disciplines.

The fellows also will play a key role in the third prong of the institute's mission: translating and disseminating results beyond academia. Traditionally, much of the learning that occurs in the nation's formal classrooms and more informal settings is not as informed by research as it could be, says Fisher. To help change that, the Science of Learning Institute recently launched partnerships with the Port Discovery Children's Museum in Baltimore and the Children's Museum of Manhattan in New York to develop exhibits that are based on the research into the science of learning. The institute also plans to hire a dissemination expert to help translate research results into classrooms and other learning settings.

The Science of Learning Institute's stated mission is "to understand and optimize the most essential part of our human capital: the ability to learn." The mission makes the institute a crucial catalyst at a university—a place dedicated to learning—where all the pieces are already in place to make major progress on one of the most important scientific questions of our time, says Landau. "One of the goals of the Science of Learning Institute," she says, "is really to sew together the parts of the university that haven't yet interacted—to make it, in President Daniels' words, one university."

Source: JHU

Parental incarceration can be worse for a child than divorce or death of a parent

Written By Unknown on Friday, January 16, 2015 | 9:16 AM


With more than 2 million people behind bars, the U.S. has the highest incarceration rate in the world. This mass incarceration has serious implications for not only the inmates, but their children, finds a new University of California-Irvine study. The study found significant health problems, including behavioral issues, in children of incarcerated parents and also that, for some types of health outcomes, parental incarceration can be more detrimental to a child's well-being than divorce or the death of a parent.

"We know that poor people and racial minorities are incarcerated at higher rates than the rest of the population, and incarceration adversely affects the health and development of children who are already experiencing significant challenges," said study author Kristin Turney, an assistant professor of sociology at UC Irvine.

When comparing children with similar demographic, socioeconomic, and familial characteristics, the study found that having a parent in prison or jail was linked to a greater incidence of attention deficit disorder/attention deficit hyperactivity disorder (ADD/ADHD), behavioral or conduct problems, learning disabilities, speech or other language problems, and developmental delays.

"The results suggest that children's health disadvantages are an overlooked and unintended consequence of mass incarceration," Turney said. "In addition, given its unequal distribution across the population, incarceration may have implications for racial and social class inequalities in children's health."

Turney will present the study at the 109th Annual Meeting of the American Sociological Association, and the research will appear in the September edition of the Journal of Health and Social Behavior.

"About 2.6 million U.S. children have a parent in state prison, federal prison, or jail at any given time," said Turney, who noted that "Sesame Street" recently introduced a Muppet named Alex, whose dad is in jail, as a way to address the stigma associated with having an imprisoned parent.

The likelihood of having an incarcerated parent is especially high in certain groups. "Among black children with fathers without a high school diploma, about 50 percent will experience parental incarceration by age 14, compared with 7 percent of white children with similarly educated fathers," Turney said.

Compared to divorce, parental incarceration is more strongly associated with both ADD/ADHD and behavioral problems in children; compared to the death of a parent, parental incarceration is more strongly associated with ADD/ADHD.

"These findings have important implications for health professionals," Turney said. 

"Physicians serving poor communities where incarceration is common may consider screening children for parental incarceration, as it is a risk factor that, in some cases, is more consequential than other forms of parental absence like divorce."

Turney's study used data from the 2011-2012 National Survey of Children's Health, a population-based and representative sample of 0- to 17-year-olds.

WHACK! Study measures head blows in girls' lacrosse

Written By Unknown on Wednesday, January 14, 2015 | 6:37 PM

Trey Crisco invited lacrosse-playing girls to the lab to measure the impact of their blows as they whacked the head of a laboratory dummy — and to evaluate the performance of protective headgear. Credit: Mike Cohea/Brown University
Lacrosse players swing hard, which is why errant stick blows are the leading cause of concussion in girls' and women's lacrosse. In a new study, researchers measured how much the worst blows accelerate the head and how much different kinds of headgear could reduce those accelerations.

Girls' and women's lacrosse is a different game from the version played by males, said Joseph Crisco, the Henry Frederick Lippitt Professor of Orthopaedic Research in the Alpert Medical School of Brown University and a researcher at Rhode Island Hospital. Females wear far less protective equipment than males do, and injuries -- especially severe head injuries -- are comparatively rare. But recently the debate about whether female players should wear headgear has gained prominence.

Coming to blows

The girls delivered peak performance averaging 60 times the acceleration of Earth's gravity (60g) when they struck the headforms with their lacrosse sticks.

"The goal of our study was to answer the question of what types of head accelerations would you see if you were hit in the head with a stick," said Crisco, who used to coach his daughters in girls lacrosse and also sits on the Sports Science and Safety Committee of US Lacrosse, the national governing body of lacrosse.

To conduct the study, published online in the Journal of Applied Biomechanics, Crisco's team asked seven female lacrosse players aged 12 to 14 to deliver at least 36 whacks each, as hard as they possibly could, to various places on two dummy headforms in the lab.

"The kinds of hits recorded were basically aggressive street fights," Crisco said. "They were really whacking at it, every shaft was broken by the end of the study, which would never happen in a game. The goal was just to give US Lacrosse and the manufacturers some baseline information on the types of accelerations they could expect to see in a worst-case scenario."

They used six different sticks, each outfitted with motion capture markers. The headforms had embedded accelerometers. In a second set of experiments the headforms donned one of four different kinds of protective headgear.

On average across 508 successful blows in the first experiment, the girls swung their sticks about 18 miles an hour, enough to complete two revolutions in less than a second. (One of Crisco's prior studies showed, perhaps not surprisingly, that high school and college players swung their sticks even faster). The peak acceleration the girls delivered to the headforms when they struck them with the shafts of their sticks averaged 60 times the acceleration of Earth's gravity (60g).

That's about three times more force than, say, football players with the kind of celebratory head butt that teammates exchange after a big play, Crisco said.

Headgear dampens blows

The second set of experiments examined what effect headgear might have on the girls' harder whacks (those with speeds around 23 miles an hour). Crisco's team measured the accelerations delivered by 20 whacks from the shaft of each volunteer's stick on both the back and the side of each headform. The headforms wore either nothing, a hard-sided men's lacrosse helmet, a rugby scrum cap, mixed martial arts headgear, or soft headgear designed for girls' and women's field hockey and lacrosse.

The average peak accelerations measured on bare headgear were 81.6g for blows to the side and 150.7g for blows to the back. The men's lacrosse helmet brought the average peak acceleration all the way down to 28.2g on the side and 23.1g on the back. The martial arts and girls lacrosse/field hockey headgear each reduced the accelerations significantly as well, but not nearly as much as the men's helmet. The rugby cap failed to reduce acceleration for blows to the side but dampened blows to the back a little better than the martial arts or lacrosse/field hockey gear.

Headgear, therefore, significantly reduced head accelerations. But Crisco cautioned against a run on headgear at the sporting goods store based on the study.

Generally research has shown that helmets do not protect against concussion -- only against skull fractures and traumatic brain injury. Indeed very little data connects accelerations to concussion risk, and individual susceptibility varies widely. Though some research hints at a figure around 100g, only the hard-sided men's helmet brought accelerations for blows to the back significantly below that figure. And in many game situations, given how little other protective equipment female players wear, Crisco said, a hard-sided helmet could easily cause more injuries that it prevents.

"It could actually make the game more aggressive," Crisco said.

 
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